Procleave webserver

Input the substrate sequence (example)


Please select the protease of interest from the dropdown menu to make the prediction: (help)


In cases where users want to predict multiple substrate sequences, we also provide a Java-based standalone version of Procleave,

which can be downloaded here: Click to Download




If you use Procleave, please kindly cite our paper:

Song J, Ho BK, Tan H, Kleifeld O, Smith AI, Pike RN, Whisstock JC (2012). Procleave: a tool for protease-specific substrate cleavage site prediction using conditional random fields, submitted for publication